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HPMC-E6

To guarantee the highest purity and efficacy, we adhere to strict global standards

Pharmaceutical Excipients

Hydroxypropyl Methylcellulose (HPMC E6)

Hydroxypropyl Methylcellulose (HPMC) is a water-soluble semisynthetic cellulose polymer, one of the most versatile and widely used multifunctional excipients globally in the pharmaceutical industry. The letter "E" signifies the type with a high Methoxyl content, while the value "6" indicates its low viscosity (typically around 6 $\text{mPa}\cdot\text{s}$ in a 2% aqueous solution). $\text{HPMC E6}$ is ideal for Film Coating, Wet Granulation, and Modified Release applications, especially for formulations requiring relatively quick dissolution and absorption.

The product conforms to the specified requirements of the United States Pharmacopeia (USP), European Pharmacopoeia (EP), and/or British Pharmacopoeia (BP).
A detailed CoA is issued with every batch, outlining potency, purity profile, and microbiological testing verification.
A comprehensive Drug Master File is available to support registration submissions to regulatory authorities worldwide.
Production takes place in certified facilities that strictly adhere to current Good Manufacturing Practices (cGMP).
Functional Class:
Film Coating Agent, Binder, Viscosity Modifier, Release Modifier.
Chemical Structure:
A cellulose ether derived from cellulose.
Solubility:
Soluble in cold water to form clear, viscous solutions.
Mechanism of Action:
As a Coating : Forms a strong, flexible film that protects the tablet and aids in swallowing.
As a Release Modifier (E6) : Due to its low viscosity, it provides a relatively rapid release of the drug, but still functions as a stabilizer or a slight release modifier compared to non-viscous binders.
Tablet Film Coating

Immediate-release and non-enteric coatings.

Its low viscosity allows for the preparation of high-concentration, sprayable coating solutions without excessive viscosity buildup.

Binder

Wet Granulation.

Provides very good binding strength, yielding robust and compressible granules.

Sterile Liquids

Eye drops and injection solutions.

High biocompatibility and ability to act as a mild viscosity agent and emulsifier in ophthalmic solutions.

Regulatory Compliance

The product fully complies with the requirements specified in the United States Pharmacopeia (USP), the European Pharmacopoeia (EP), and/or other relevant standards (including the designation $\text{Hypromellose}$)., and/or British Pharmacopoeia (BP).

Viscosity

Strict control over the nominal viscosity (6 $\text{mPa}\cdot\text{s}$ for a 2% solution) is maintained to ensure consistent performance as a coating agent or binder.

Chemical Composition

Accurate determination of the Methoxyl and Hydroxypropoxyl Content ratio to ensure the specific functional characteristics of the E-type.

Manufacturing Operations

Production is conducted in a rigorous cGMP environment, ensuring consistency in physical properties (e.g., particle size).

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