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Hydroxypropyl Methylcellulose (HPMC) is a water-soluble semisynthetic cellulose polymer, one of the most versatile and widely used multifunctional excipients globally in the pharmaceutical industry. The letter "E" signifies the type with a high Methoxyl content, while the value "6" indicates its low viscosity (typically around 6 $\text{mPa}\cdot\text{s}$ in a 2% aqueous solution). $\text{HPMC E6}$ is ideal for Film Coating, Wet Granulation, and Modified Release applications, especially for formulations requiring relatively quick dissolution and absorption.
Immediate-release and non-enteric coatings.
Its low viscosity allows for the preparation of high-concentration, sprayable coating solutions without excessive viscosity buildup.
Wet Granulation.
Provides very good binding strength, yielding robust and compressible granules.
Eye drops and injection solutions.
High biocompatibility and ability to act as a mild viscosity agent and emulsifier in ophthalmic solutions.
The product fully complies with the requirements specified in the United States Pharmacopeia (USP), the European Pharmacopoeia (EP), and/or other relevant standards (including the designation $\text{Hypromellose}$)., and/or British Pharmacopoeia (BP).
Strict control over the nominal viscosity (6 $\text{mPa}\cdot\text{s}$ for a 2% solution) is maintained to ensure consistent performance as a coating agent or binder.
Accurate determination of the Methoxyl and Hydroxypropoxyl Content ratio to ensure the specific functional characteristics of the E-type.
Production is conducted in a rigorous cGMP environment, ensuring consistency in physical properties (e.g., particle size).