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Poly vinyl
pyrrolidone

To guarantee the highest purity and efficacy, we adhere to strict global standards

Pharmaceutical Excipients

Polyvinylpyrrolidone (PVP)

Polyvinylpyrrolidone (PVP) is a synthetic, water-soluble pharmaceutical excipient characterized by its excellent biocompatibility and strong film-forming properties. PVP is a multifunctional excipient, primarily used as a Binder in tablets, a Dispersant and Stabilizer for Solid Dispersions, and a carrier for APIs with poor aqueous solubility. The different grades (such as K30 and K90) are defined by their K-value, which relates to their average molecular weight and viscosity.

The product conforms to the specified requirements of the United States Pharmacopeia (USP), European Pharmacopoeia (EP), and/or British Pharmacopoeia (BP).
A detailed CoA is issued with every batch, outlining potency, purity profile, and microbiological testing verification.
A comprehensive Drug Master File is available to support registration submissions to regulatory authorities worldwide.
Production takes place in certified facilities that strictly adhere to current Good Manufacturing Practices (cGMP).
Functional Class:
Binder, Solid Dispersion Solvent/Stabilizer, Film Former.
Chemical Structure:
Synthetic polymer of $\text{N-vinyl-2-pyrrolidone}$.
Mechanism of Action:
Enhances cohesion between powder particles (as a binder) and improves drug solubility by preventing API recrystallization in solid dispersions.
Compatibility:
Compatible with a wide range of organic and inorganic APIs and excipients.
PVP K30

40,000 - 55,000 Daltons

Standard Binder for wet granulation, and a solid dispersion agent via spray drying.

PVP K90

1,000,000 - 1,500,000 Daltons

Very Strong Binder for wet granulation (at lower concentrations), and a film former for dermal or mucoadhesive patches.

PVP K12/K17

Lower Molecular Weight

Solid solutions, and tablet sugar coating.

Regulatory Compliance

The product fully complies with the requirements specified in the United States Pharmacopeia (USP), the European Pharmacopoeia (EP), and/or other relevant standards.

K-Value and Viscosity

Strict control over the K-value and viscosity (in a standard aqueous solution) is maintained to ensure consistent binding strength in tablets.

Purity and Impurity Control)

Control over monomer content (NVP), water, and moisture.

Manufacturing Operations

Production is conducted in a rigorous cGMP environment, ensuring consistency in physicochemical properties.

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