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Propylene
Glycol

To guarantee the highest purity and efficacy, we adhere to strict global standards

Pharmaceutical Excipients

Propylene Glycol (PG)

Propylene Glycol (PG) is a colorless, odorless, organic diol (a compound containing two hydroxyl groups) characterized by its highly hygroscopic nature and excellent biocompatibility. $\text{PG}$ is one of the most important liquid excipients in pharmaceutical formulations, primarily serving as a Solvent, a Vehicle for lipid-soluble or poorly water-soluble Active Pharmaceutical Ingredients (APIs), and a Humectant in topical preparations. It is a key component in oral solutions, topical preparations, and emulsified drug delivery systems.

The product conforms to the specified requirements of the United States Pharmacopeia (USP), European Pharmacopoeia (EP), and/or British Pharmacopoeia (BP).
A detailed CoA is issued with every batch, outlining potency, purity profile, and microbiological testing verification.
A comprehensive Drug Master File is available to support registration submissions to regulatory authorities worldwide.
Production takes place in certified facilities that strictly adhere to current Good Manufacturing Practices (cGMP).
Functional Class:
Solvent, Vehicle, Humectant, Penetration Enhancer.
Chemical Structure:
$\text{Propane-1,2-diol}$ ($\text{C}_3\text{H}_8\text{O}_2$).
Solubility:
Completely miscible with water, ethanol, chloroform, and many essential oils.
Mechanism of Action:
As a Solvent : Enhances the solubility of many lipophilic (hydrophobic) APIs, especially in hydroalcoholic formulations.
As a Vehicle : Provides a stable and suitable medium for drug delivery in oral and topical solutions.
As a Humectant : Reduces moisture loss when used in topical preparations, helping to keep skin hydrated.
Oral Solutions

Solvent for APIs in syrups and oral drops.

Improves the taste and solubility of the drug, and helps maintain formulation stability.

Topical/Dermal Preparations

Creams, ointments, and dermal solutions.

Acts as a humectant to prevent skin dryness and a penetration enhancer to aid drug absorption through the skin.

Injections and IV Drugs

Cosolvent for the preparation of sterile injectables.

Its stability and safety make it suitable for sterile formulations, though it must be used within specific concentration limits.

Soft Gelatin Capsules

Vehicle for liquid filling of capsules.

Compatible with the gelatin shell.

Regulatory Compliance

The product fully complies with the requirements specified in the United States Pharmacopeia (USP), the European Pharmacopoeia (EP), and/or other relevant standards.

Purity and Impurity Control

Strict control over product purity, focusing on the minimum content of toxic impurities such as Ethylene Glycol and Diethylene Glycol.

Chemical Analysis)

Accurate determination of the product's viscosity and density to ensure consistent performance as a solvent.

Manufacturing Operations

Production is conducted in a rigorous cGMP environment, ensuring consistency in physicochemical properties.

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