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Sucralose
USP/EP

We supply Sucralose in high-purity grades to ensure optimal taste and stability in your formulation .

Pharmaceutical Excipients

Sucralose

Sucralose is a High-Intensity Artificial Sweetener, derived from sucrose (table sugar) through a selective process that replaces three hydroxyl groups with chlorine atoms. Sucralose is one of the most potent sweeteners available, offering superior sweetness ranging from 400 to 800 times that of sucrose, with the unique advantage of Excellent Thermal and Chemical Stability. Sucralose is primarily used to mask the unpleasant taste of medications and enhance patient acceptance, making it ideal for formulations that require heat processing or have a long shelf life.

The product fully complies with the requirements specified in the United States Pharmacopeia (USP), the European Pharmacopoeia (EP), and/or other food/supplementary standards (FCC).
Rigorous testing of Sucralose purity and sweetening intensity.
Close monitoring of residual sucrose and organic chlorides content to ensure safety.
Production is conducted in a rigorous cGMP environment, ensuring consistency in physicochemical properties.
Functional Class:
High-Intensity Sweetener, Flavoring Agent.
Chemical Structure:
$\text{1,6-dichloro-1,6-dideoxy-}\beta \text{-D-fructofuranosyl-4-chloro-4-deoxy-}\alpha \text{-D-galactopyranoside}$
Sweetening Power:
sim 400 - 800 times sweeter than Sucrose.
Mechanism of Action:
As a Sweetener : Provides a pure sweet taste, free from the lingering aftertaste that may be associated with other sweeteners.
Thermal Stability : Does not degrade under high temperatures (such as sterilization or granulation), making it safe for use across all manufacturing processes.
Chemical Stability : Stable across a wide range of pH levels, especially in acidic environments, and is resistant to hydrolysis.
Products Requiring Sterilization

Liquid solutions that undergo heat sterilization.

Its thermal stability ensures that the sweetening power remains unchanged.

Oral Tablets

Chewable tablets, effervescent tablets, and dry powder dosage forms (sachets).

Requires a very low dose for the required sweetness, making it cost-effective.

Solutions and Syrups

Liquid medicines requiring stability at an acidic pH (e.g., acid-based formulations).

Solves the issue of degradation faced by other sweeteners in acidic conditions.

Nutritional Supplements

An excellent sugar replacement in all types of supplements.

It is Non-Caloric and does not raise blood glucose levels.

Regulatory Compliance

The product fully complies with the requirements specified in the United States Pharmacopeia (USP), the European Pharmacopoeia (EP), and/or other food/supplementary standards (FCC).

Sweetening Power and Purity

Rigorous testing of Sucralose purity and sweetening intensity.

Impurities

Close monitoring of residual sucrose and organic chlorides content to ensure safety.

Manufacturing Operations

Production is conducted in a rigorous cGMP environment, ensuring consistency in physicochemical properties.

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