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Thiamine
Vitamins B1

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Vitamins

Thiamine/Vitamins B1

Thiamine is an essential water-soluble vitamin, widely known as Vitamin B1. It is a crucial component in energy metabolism, playing a key role as a cofactor in the conversion of carbohydrates into energy. We supply Thiamine (typically as the highly soluble Hydrochloride or the more stable Nitrate salt) in ultra-pure grades, suitable for pharmaceutical formulations, nutritional supplements, and injectable solutions for acute deficiency treatment.

The product conforms to the specified requirements of the United States Pharmacopeia (USP), European Pharmacopoeia (EP), and/or British Pharmacopoeia (BP).
A detailed CoA is issued with every batch, outlining potency, purity profile, and microbiological testing verification.
A comprehensive Drug Master File is available to support registration submissions to regulatory authorities worldwide.
Production takes place in certified facilities that strictly adhere to current Good Manufacturing Practices (cGMP).
Therapeutic Class:
Essential Vitamin (B1) and Metabolic Cofactor.
Mechanism of Action:
Converted to its active form, Thiamine Pyrophosphate (TPP), which is an essential cofactor for enzymes involved in glucose metabolism and energy production (e.g., pyruvate dehydrogenase).
Clinical Application:
Prevention and treatment of Thiamine deficiency (Beriberi), treatment of Wernicke-Korsakoff syndrome (due to severe deficiency, often alcohol-related), and nervous system function support.
Competitive Advantage:
A vital API for supporting neurological metabolism and energy production, indispensable in multivitamin formulations and parenteral nutritional solutions.
Tablets and Capsules

Immediate-release tablets and multivitamin supplements.

API powder offers good flow and compressibility characteristics for standard tableting and encapsulation processes.

Sterile Liquid Formulations

Intravenous (IV) and Intramuscular (IM) injectable solutions.

The Hydrochloride salt is the preferred form for injections due to its high solubility and stability in sterile aqueous solutions.

Oral Liquid Formulations

Syrups and multivitamin solutions.

The API's strong, characteristic flavor must be considered for effective flavor masking during formulation to ensure patient compliance.

Regulatory Compliance

The product conforms to the specified requirements of the United States Pharmacopeia (USP), European Pharmacopoeia (EP), and/or British Pharmacopoeia (BP).

Certificate of Analysis (CoA)

A detailed CoA is issued with every batch, outlining potency, purity profile, and microbiological testing verification.

Drug Master File (DMF)

A comprehensive Drug Master File is available to support registration submissions to regulatory authorities worldwide.

Manufacturing Operations

Production takes place in certified facilities that strictly adhere to current Good Manufacturing Practices (cGMP).

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